• Microfluidic In Vitro Platform for (Nano)Safety and (Nano)Drug Efficiency Screening 

      Kohl, Yvonne; Biehl, Margit; Spring, Sarah; Hesler, Michelle; Ogourtsov, Vladimir; Todorovic, Miomir; Owen, Joshua; Elje, Elisabeth; Kopecka, Kristina; Moriones, Oscar Hernando; Bastus, Neus G.; Simon, Peter; Dubaj, Tibor; Rundén-Pran, Elise; Puntes, Victor; William, Nicola; von Briesen, Hagen; Wagner, Sylvia; Kapur, Nikil; Mariussen, Espen; Nelson, Andrew; Gabelova, A; Dusinska, Maria; Velten, Thomas; Knoll, Thorsten (Peer reviewed; Journal article, 2021)
      Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular and organ level responses for rapid and animal‐free risk assessment of new chemicals and drugs. Microfluidic cell‐based devices ...
    • Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation 

      Dubaj, Tibor; Kozics, Katarina; Srámková, Monika; Manova, Alena; Bastus, Neus G.; Moriones, Oscar H.; Kohl, Yvonne; Dusinska, Maria; Rundén-Pran, Elise; Puntes, Victor; Nelson, Andrew; Gábelová, Alena; Simon, Peter (Peer reviewed; Journal article, 2022)
      Data suitable for assembling a physiologically-based pharmacokinetic (PBPK) model for nanoparticles (NPs) remain relatively scarce. Therefore, there is a trend in extrapolating the results of in vitro and in silico studies ...
    • Rapid identification of in vitro cell toxicity using an electrochemical membrane screening platform 

      Kohl, Yvonne; William, Nicola; Elje, Elisabeth; Backes, Nadine; Rothbauer, Mario; Srancikova, Annamaria; Rundén-Pran, Elise; El Yamani, Naouale; Korenstein, Rafi; Madi, Lea; Barbul, Alexander; Kozics, Katarina; Sramkova, Monika; Steenson, Karen; Gabelova, Alena; Ertl, Peter; Dusinska, Maria; Nelson, Andrew (Peer reviewed; Journal article, 2023)
      This study compares the performance and output of an electrochemical phospholipid membrane platform against respective in vitro cell-based toxicity testing methods using three toxicants of different biological action ...
    • Safety-by-design and engineered nanomaterials: the need to move from theory to practice 

      Trump, Benjamin D.; Antunes, Dalila; Palma-Oliveira, José; Nelson, Andrew; Hudecova, Alexandra Misci; Rundén-Pran, Elise; Dusinska, Maria; Gispert, Ignasi; Resch, Susanne; Alfaro-Serrano, Beatriz; Afantitis, Antreas; Melagraki, Georgia; Tse, Edmund C. M.; Trump, Josh; Kohl, Yvonne; Linkov, Igor (Peer reviewed; Journal article, 2023)
      As the governance of engineered nanomaterials (ENMs) evolves, innovations in the prevention, mitigation, management, and transfer of risk shape discussion of how nanotechnology may mature and reach various marketplaces. ...